A Secret Weapon For ceesdekker

A Secret Weapon For ceesdekker

Blog Article

‘The next is nanopores, that's our oldest line of exploration and that has now resulted in DNA sequencers based upon nanopores. We pull particular person DNA strands by way of a nanopore and may then study off the nucleotide sequence. Very lately, we even managed to read out a single protein for The 1st time working with This system. But this line of exploration is not simply about establishing equipment, but additionally about real Organic inquiries.

But how do morality, the dignity with the human being, my encounter of your this means of lifetime, comply with from your motion of atoms? A purely naturalistic point of view fails right here; a Christian standpoint, I feel, is a much more fair technique to interpret these elements of truth.’

, Groningen researchers current the final results in their endeavours to make labs much more sustainable and provide strategies for other labs. 

A rhythmically pulsing leaf-spring DNA-origami nanoengine that drives a passive follower Mathias Centola

This yielded a breakthrough. In just just a few months, we were being capable to measure transportation via somebody single-walled carbon nanotube. Based upon minimal-temperature experiments by a superb PhD pupil in my team, Sander Tans (now a valued colleague and professor at Delft University of Know-how with the Energetic research lab at AMOLF in Amsterdam), we showed that carbon nanotubes were being real quantum wires with incredibly lengthy (micrometres) Digital coherence lengths — confirming theoretical predictions of metallic conduct.

Electrical transportation in monolayers of phthalocyanine molecular wires and AFM imaging of a single wire bridging two electrodes

All parameters have been the exact same for every panel in this video, except for the Preliminary placement in the 6hb rod (demonstrated in blue) over the nanopore. Simulations that terminated early due to translocation from the rod with the pore are marked by a grey track record.

Learning DNA loop extrusion by cees dekker SMC proteins for chromosome architecture with one-molecule assays.

‘Of course, I understand persons were stunned at some time. At the end of the nineties, Once i was in my forties, I had been Professor of Molecular Electronics and I have to confess that it experienced become a bit bored, I didn’t master Significantly anymore. The sphere went much more into the appliance facet, how you can integrate nanotubes into Digital circuits.

Resolving the phase measurement in condensin-driven DNA loop extrusion identifies ATP binding because the step-creating approach

Instance (4) of bending configurations in 3D simulations of DNA rods on nanopores. A percentage of the membrane is demonstrated in grey, the rim from the pore is highlighted in pink, in addition to a 3D rendering with the motion of the DNA rod is exhibited.

Afterwards we spoke once again briefly for the reason that Dekker felt that our discussion of his faith swiftly grew to become purely philosophical, While In addition it concretely helps him in his perform.

Developments in nanotechnology inside the nineties created constructing electronic units from solitary molecules a likelihood. Cees Dekker recounts how his crew developed a area-temperature transistor depending on an individual carbon nanotube.

Supercoiling-dependent DNA binding: quantitative modeling and apps to bulk and single-molecule experiments